Drug details:
Molecular formula: C₁₇H₁₈ClN₃O₅

Standard name: 1-(3-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]urea

Curated SMILES: COC1=CC(C(=O)NNC(=O)NC2=CC(Cl)=CC=C2)=CC(OC)=C1OC

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: DGC
Drug effect: Inhibits of diguanylate cyclase (DGC) enzymes that synthesize c-di-GMP that is essential for biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Sambanthamoorthy K, et al., 2015. Modulating Acinetobacter baumannii biofilm development with molecules containing 3,4,5-trimethoxy-N,N',N'-trimethylbenzohydrazide moiety. Bioorg Med Chem Lett 25(10):2238-42.