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Compound category: N-phenylureas
(total 6 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
1-(3-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]urea Depiction based on curated SMILES CH 3 O CH 3 O Cl CH 3 N H O N H HN O O Acinetobacter Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett
1-(4-chlorophenyl)-3-[3-(trifluoromethyl)phenyl]urea Depiction based on curated SMILES F F F Cl NH O N H Bacillus Nutritional/Metabolic factor Preclinical (in vitro) Fernandes AS, et al. 2021. Front Microbiol
1-[[5-tert-butyl-2-[(4-fluorophenyl)methyl]pyrazole-3-carbonyl]amino]-3-phenylurea Depiction based on curated SMILES HN O N H HN O CH 3 F N N H 3 C H 3 C Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea Depiction based on curated SMILES O NH N H N N S Shigella VirF Preclinical (in vitro) Hurt JK, et al. 2010. J Biomol Screen; Emanuele AA, et al. 2014. J Antibiot (Tokyo); Emanuele AA, et al. 2015. PLoS One
Imidocarb Depiction based on curated SMILES O NH N NH N H NH N Escherichia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Pan NJ, et al. 2009. Antimicrob Agents Chemother
N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-N'-(3,4-dimethylphenyl)urea Depiction based on curated SMILES CH 3 CH 3 N O H 3 C N N CH 3 N H O N H Yersinia TTSS (Type III secretion system) Preclinical (in vitro) Harmon DE, et al. 2010. Antimicrob Agents Chemother
   
   
   
   
   
   
   
   
   


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