Drug details:
Molecular formula: C₂₂H₂₄FN₅O₂

Standard name: 1-[[5-tert-butyl-2-[(4-fluorophenyl)methyl]pyrazole-3-carbonyl]amino]-3-phenylurea

Curated SMILES: CC(C)(C)C1=NN(CC2=CC=C(F)C=C2)C(C(=O)NNC(=O)NC2=CC=CC=C2)=C1

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Motility
Target: Not determined
Drug effect: Inhibits sliding motility and then results in a decrease in bacterial virulence.
Max phase: Preclinical (in vitro)
Publication:
Ouertatani-Sakouhi H, et al., 2017. Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One 12(7):e0181121.