Drug details:
Molecular formula: C₁₉H₂₀N₆O

Standard name: 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea

Synonyms:

1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea Imidocarbum Imidocarbe Imidocarbo 1,3-Bis(3-(2-imidazolin-2-yl)phenyl)urea Imidocarb [INN:BAN] N,N'-Bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea Imidocarbe [INN-French] Imidocarbum [INN-Latin] ......

Curated SMILES: C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NC3=CC=CC(=C3)C4=NCCN4

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Secretion of the EPEC effector Tir was significantly reduced.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.