Drug details:
Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;

Curated SMILES: NC1=NC=C(C2=CC=C(NC(=O)C3=CN=C(NCCC4=CC=CC=C4)N=C3)C=C2)N1

Evidence for compound's anti-virulence activity:

Clostridium
Related VFcategory: Exotoxin; Regulation
Target: Not determined
Drug effect: Targets two-component systems to interfere with signaling pathways thereby inhibiting virulence responses such as antibiotic resistance, toxin secretion and biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Thanissery R, et al., 2018. A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile. Front Microbiol 9:1206.