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4-Methoxy-beta-nitrostyrene

Drug details:
Molecular formula: C9H9NO3

Classification: Anisoles; Phenol ethers; Benzenoids; Organic compounds;
Synonyms:  1-methoxy-4-(2-nitrovinyl)benzene
(E)-1-methoxy-4-(2-nitrovinyl)benzene
1-Methoxy-4-[(E)-2-nitroethenyl]benzene
1-(4-Methoxyphenyl)-2-nitroethylene
p-(2-Nitrovinyl)anisole
trans-4-Methoxy-beta-nitrostyrene
2'-Nitro vinyl anisole
4-(2-Nitrovinyl)anisole
1-(4-methoxyphenyl)-2-nitroethene
......

Chemical structure:
Depiction based on curated SMILES CH 3 O + N O _ O

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publication:
Hurt JK, et al., 2010. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. J Biomol Screen 15(4):379-87.








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