|
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-[(4-methoxyphenyl)methyl]pyrrole-2-carboxamide;hydrochloride |
|
Acinetobacter |
Biofilm |
Preclinical (in vitro) |
Richards JJ, et al. 2008. Bioorg Med Chem Lett |
|
1-(4-chlorophenoxy)-3-(2,6-dimethylpiperidin-1-yl)propan-2-ol |
Depiction based on curated SMILES
OH
Cl
O
CH
3
N
CH
3
|
Bacillus |
Nutritional/Metabolic factor |
Preclinical (in vitro) |
Fernandes AS, et al. 2021. Front Microbiol |
|
1-[4-(2,3,5-trimethylphenoxy)butyl]piperidine |
Depiction based on curated SMILES
CH
3
CH
3
CH
3
N
O
|
Bacillus |
Nutritional/Metabolic factor |
Preclinical (in vitro) |
Fernandes AS, et al. 2021. Front Microbiol |
|
[2-hydroxy-3-(2,4,6-trimethylphenoxy)propyl]-(2,4,4-trimethylpentan-2-yl)azanium |
Depiction based on curated SMILES
H
H
3
C
CH
3
H
3
C
H
3
C
CH
3
CH
3
H
CH
3
+
N
HO
O
H
3
C
|
Bacillus |
Nutritional/Metabolic factor |
Preclinical (in vitro) |
Fernandes AS, et al. 2021. Front Microbiol |
|
(3s)-3-Amino-1-[4-(Benzyloxy)phenyl]-4-(1h-Imidazol-4-Yl)butan-2-One |
Depiction based on curated SMILES
O
NH
2
O
N
HN
H
|
Brucella |
Others |
Preclinical (in vitro) |
Abdo MR, et al. 2011. Org Biomol Chem |
|
PB-2.12 (internal name in literature) |
Depiction based on curated SMILES
H
2
N
Cl
Cl
O
NH
2
O
H
3
C
O
O
|
Clostridium Streptococcus |
theta-toxin/PFO (Perfringolysin O) Pneumolysin |
Preclinical (in vitro) Preclinical (in vitro) |
Aziz UBA, et al. 2024. Nat Commun
|
|
4-(4-methoxyphenyl)-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole |
Depiction based on curated SMILES
N
S
H
3
C
N
S
O
|
Enterococcus Staphylococcus |
Others; Adherence; Biofilm Others; Adherence; Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Oniga SD, et al. 2017. Molecules
|
|
ethyl 2-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-1-phenylpyrazol-3-yl]acetate |
Depiction based on curated SMILES
Br
H
3
C
O
H
3
C
O
N
N
O
O
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
5beta,6alpha-Bis[4-(4-methoxyphenyl)-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine |
Depiction based on curated SMILES
N
N
N
O
CH
3
N
H
H
2
N
N
N
N
N
O
H
3
C
|
Pseudomonas |
Biofilm |
Preclinical (in vitro) |
Huigens RW 3rd, et al. 2009. Org Biomol Chem |
|
4-Methoxy-beta-nitrostyrene |
Depiction based on curated SMILES
CH
3
O
+
N
O
_
O
|
Shigella |
VirF |
Preclinical (in vitro) |
Hurt JK, et al. 2010. J Biomol Screen |
|
| | |