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Compound category: Phenol ethers
(total 10 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-[(4-methoxyphenyl)methyl]pyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES Br ClH NH 2 HN N HN O Br H 3 C N O Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
1-(4-chlorophenoxy)-3-(2,6-dimethylpiperidin-1-yl)propan-2-ol Depiction based on curated SMILES OH Cl O CH 3 N CH 3 Bacillus Nutritional/Metabolic factor Preclinical (in vitro) Fernandes AS, et al. 2021. Front Microbiol
1-[4-(2,3,5-trimethylphenoxy)butyl]piperidine Depiction based on curated SMILES CH 3 CH 3 CH 3 N O Bacillus Nutritional/Metabolic factor Preclinical (in vitro) Fernandes AS, et al. 2021. Front Microbiol
[2-hydroxy-3-(2,4,6-trimethylphenoxy)propyl]-(2,4,4-trimethylpentan-2-yl)azanium Depiction based on curated SMILES H H 3 C CH 3 H 3 C H 3 C CH 3 CH 3 H CH 3 + N HO O H 3 C Bacillus Nutritional/Metabolic factor Preclinical (in vitro) Fernandes AS, et al. 2021. Front Microbiol
(3s)-3-Amino-1-[4-(Benzyloxy)phenyl]-4-(1h-Imidazol-4-Yl)butan-2-One Depiction based on curated SMILES O NH 2 O N HN H Brucella Others Preclinical (in vitro) Abdo MR, et al. 2011. Org Biomol Chem
PB-2.12
(internal name in literature)
Depiction based on curated SMILES H 2 N Cl Cl O NH 2 O H 3 C O O Clostridium
Streptococcus
theta-toxin/PFO (Perfringolysin O)
Pneumolysin
Preclinical (in vitro)
Preclinical (in vitro)
Aziz UBA, et al. 2024. Nat Commun
4-(4-methoxyphenyl)-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole Depiction based on curated SMILES N S H 3 C N S O Enterococcus
Staphylococcus
Others; Adherence; Biofilm
Others; Adherence; Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Oniga SD, et al. 2017. Molecules
ethyl 2-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-1-phenylpyrazol-3-yl]acetate Depiction based on curated SMILES Br H 3 C O H 3 C O N N O O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
5beta,6alpha-Bis[4-(4-methoxyphenyl)-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N N N O CH 3 N H H 2 N N N N N O H 3 C Pseudomonas Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
4-Methoxy-beta-nitrostyrene Depiction based on curated SMILES CH 3 O + N O _ O Shigella VirF Preclinical (in vitro) Hurt JK, et al. 2010. J Biomol Screen
   


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