Drug details:
Molecular formula: C₂₀H₃₆NO₂⁺

Standard name: [2-hydroxy-3-(2,4,6-trimethylphenoxy)propyl]-(2,4,4-trimethylpentan-2-yl)azanium

Curated SMILES: CC1=CC(C)=C(OCC(O)C[NH2+]C(C)(C)CC(C)(C)C)C(C)=C1

Evidence for compound's anti-virulence activity:

Bacillus
Related VFcategory: Nutritional/Metabolic factor
Target: KtrAB
Drug effect: Inhibits KtrAB ion channel complex, a component of the K+ homeostasis machinery to interfere with pathogen survival in host cells.
Max phase: Preclinical (in vitro)
Publication:
Fernandes AS, et al., 2021. Fluorometric Liposome Screen for Inhibitors of a Physiologically Important Bacterial Ion Channel. Front Microbiol 12:603700.