Drug details:
Molecular formula: C₁₈H₂₉NO

Standard name: 1-[4-(2,3,5-trimethylphenoxy)butyl]piperidine

Curated SMILES: CC1=CC(OCCCCN2CCCCC2)=C(C)C(C)=C1

Evidence for compound's anti-virulence activity:

Bacillus
Related VFcategory: Nutritional/Metabolic factor
Target: KtrAB
Drug effect: Inhibits KtrAB ion channel complex, a component of the K+ homeostasis machinery to interfere with pathogen survival in host cells.
Max phase: Preclinical (in vitro)
Publication:
Fernandes AS, et al., 2021. Fluorometric Liposome Screen for Inhibitors of a Physiologically Important Bacterial Ion Channel. Front Microbiol 12:603700.