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Tremerad

Drug details:
Molecular formula: C15H10ClI2NO3

Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Synonyms:  Benzamide, 2-(acetyloxy)-N-(4-chlorophenyl)-3,5-diiodo-
Clioxanida
Clioxanidum
Clioxanidum [INN-Latin]
Clioxanida [INN-Spanish]
4'-Chloro-3,5-diiodosalicylanilide acetate
2-Acetoxy-3,5-diiodo-4'-chlorobenzanilide
2-Acetoxy-4'-chloro-3,5-di-iodobenzanilide
EINECS 238-414-0
......

Chemical structure:
Depiction based on curated SMILES I I Cl H 3 C NH O O O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Kauppi AM, et al., 2003. Targeting bacterial virulence: inhibitors of type III secretion in Yersinia. Chem Biol 10(3):241-9.








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