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2-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-5-chloro-N-(3,4-dichlorophenyl)benzamide

Drug details:
Molecular formula: C19H11Cl3N4O3S2

Classification: Anilides; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES Cl Cl N H O Cl N H O O S N S N

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Kauppi AM, et al., 2003. Targeting bacterial virulence: inhibitors of type III secretion in Yersinia. Chem Biol 10(3):241-9.








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