Drug details:
Molecular formula: C₃₄H₂₄N₂O₂

Standard name: 4-[4,5-bis(4-phenylphenyl)-1H-imidazol-2-yl]benzoic acid

Synonyms:

4-(4,5-di(biphenyl-4-yl)-1H-imidazol-2-yl)benzoic acid 4-[4,5-di(biphenyl-4-yl)-1H-imidazol-2-yl]benzoic acid 4-(4,5-dibiphenyl-4-yl-1{H}-imidazol-2-yl)benzoic acid

Curated SMILES: O=C(O)C1=CC=C(C2=NC(C3=CC=C(C4=CC=CC=C4)C=C3)=C(C3=CC=C(C4=CC=CC=C4)C=C3)N2)C=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Hu X, et al., 2013. Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches. Bioorg Med Chem Lett 23(4):1056-62.