|
2-hydroxy-N-[(Z)-1-(4-phenylphenyl)ethylideneamino]benzamide |
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
3-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]-N-methylbenzamide |
Depiction based on curated SMILES
O
OH
OH
HO
HO
H
3
C
OH
H
O
NH
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
3-[4-[(S)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]-N-methylbenzamide |
Depiction based on curated SMILES
O
OH
HO
HO
OH
H
3
C
OH
O
N
H
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
Methyl 3-[4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]sulfanylphenyl]benzoate |
Depiction based on curated SMILES
OH
OH
HO
HO
H
3
C
O
S
O
O
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
Methyl 3-[4-[[(2S,3S,4S,5S,6R)-3,4,5-trihyd roxy-6-(hyd roxymethyl)tetrahydropyran-2-yl]amino]phenyl]benzoate |
Depiction based on curated SMILES
OH
OH
HO
HO
H
3
C
O
N
H
O
O
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
N-methyl-3-[4-[[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]benzamide |
Depiction based on curated SMILES
OH
OH
HO
HO
H
3
C
O
O
NH
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-[4-(4-methoxyphenyl)phenyl]butan-2-one |
Depiction based on curated SMILES
NH
2
NH
N
H
O
CH
3
O
|
Brucella |
Others |
Preclinical (in vitro) |
Abdo MR, et al. 2011. Org Biomol Chem |
|
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-[4-(4-methylphenyl)phenyl]butan-2-one |
Depiction based on curated SMILES
H
2
N
N
H
N
H
O
CH
3
|
Brucella |
Others |
Preclinical (in vitro) |
Abdo MR, et al. 2011. Org Biomol Chem |
|
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-[4-[4-(trifluoromethyl)phenyl]phenyl]butan-2-one |
Depiction based on curated SMILES
N
F
F
F
H
2
N
N
H
H
O
|
Brucella |
Others |
Preclinical (in vitro) |
Abdo MR, et al. 2011. Org Biomol Chem |
|
5-[2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]isoxazole-3-carboxylic acid |
Depiction based on curated SMILES
OH
O
O
N
F
F
F
F
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Soellner MB, et al. 2007. J Am Chem Soc |
|
| | |