Drug details:
Molecular formula: C₂₁H₁₈N₂O₂

Standard name: 2-hydroxy-N-[(Z)-1-(4-phenylphenyl)ethylideneamino]benzamide

Curated SMILES: C/C(=N/NC(=O)C1=CC=CC=C1O)/C2=CC=C(C=C2)C3=CC=CC=C3

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.