Drug details:
Molecular formula: C₂₀H₂₂O₇S

Standard name: methyl 3-[4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylphenyl]benzoate

Curated SMILES: COC(=O)C1=CC(C2=CC=C(SC3OC(CO)C(O)C(O)C3O)C=C2)=CC=C1

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Inhibitis FimH function and activity to circumvent bacterial bladder cell adhesion, invasion, and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Mydock-McGrane L, et al., 2016. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J Med Chem 59(20):9390-9408.