Drug details:
Molecular formula: C₁₅H₁₂N₂O₂S

Standard name: 5-cyano-6-[(4-methylphenyl)methylsulfanyl]pyridine-2-carboxylic acid

Curated SMILES: CC1=CC=C(CSC2=C(C#N)C=CC(C(=O)O)=N2)C=C1

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Secretion of the EPEC effector Tir was significantly reduced.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.