Drug details:
Molecular formula: C₁₄H₁₃N₅O₃

Standard name: N-[[amino(pyridin-2-yl)methylidene]amino]-5-methyl-2-nitrobenzamide

Curated SMILES: CC1=CC=C([N+](=O)[O-])C(C(=O)NNC(=N)C2=CC=CC=N2)=C1

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.