Home
Search
Category
Compounds
Status
Download
Contacts
Resources



3-hydroxy-N-[(Z)-[5-(2-nitrophenyl)furan-2-yl]methylideneamino]benzamide

Drug details:
Molecular formula: C18H13N3O5

Classification: Nitrobenzenes; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES NH _ O O + N OH O N O

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Smith MA, et al., 2012. Identification of the binding site of Brucella VirB8 interaction inhibitors. Chem Biol 19(8):1041-8.








Back to Top
Back to Top
2004-2024 NIPB, CAMS&PUMC