Drug details:
Molecular formula: C₁₄H₁₃BrN₄

Standard name: 4-(6-bromo-1-ethylindol-3-yl)pyrimidin-2-amine

Curated SMILES: CCN1C=C(C2=CC=NC(N)=N2)C2=CC=C(Br)C=C21

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation and increases the potency of colistin.
Max phase: Preclinical (in vitro)
Publication:
Huggins WM, et al., 2018. Meridianin D Analogues Display Antibiofilm Activity against MRSA and Increase Colistin Efficacy in Gram-Negative Bacteria. ACS Med Chem Lett 9(7):702-707.