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Compound category: Benzoic acids and derivatives
(total 49 related compounds in database, current show from 21 to 30)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
5beta,6alpha-Bis[4-(benzoylaminomethyl)-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES O N H N HN N N N N H N H N H 2 N N H O Pseudomonas Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
Mefenamic acid Depiction based on curated SMILES H 3 C HO O CH 3 N H Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
3,4-DIMETHYLBENZOIC ACID Depiction based on curated SMILES CH 3 O HO CH 3 Salmonella TTSS (SPI-1 encode) Preclinical (in vitro) Peixoto RJM, et al. 2017. Appl Environ Microbiol
(E)-N'-(2,3,4-Trihydroxybenzylidene)benzohydrazide Depiction based on curated SMILES OH OH O HO N N H Escherichia
Salmonella		 TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vitro)
Preclinical (in vitro)		 Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
Negrea A, et al. 2007. Antimicrob Agents Chemother
N'-(3,5-dichloro-2-hydroxybenzylidene)benzohydrazide Depiction based on curated SMILES OH Cl O Cl N N H Escherichia
Salmonella		 TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vitro)
Preclinical (in vitro)		 Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
Negrea A, et al. 2007. Antimicrob Agents Chemother
2-morpholin-4-yl-5-(3-thiophen-2-ylprop-2-ynoylamino)benzoic acid Depiction based on curated SMILES N H OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(2e)-3-(2-thienyl)prop-2-enoyl]amino]benzamide Depiction based on curated SMILES N H NH 2 O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES N H OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(Z)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES HN OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-piperidin-1-yl-5-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES N H OH O S O N Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
   


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