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Compound category: Benzoic acids and derivatives
(total 49 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-cyclopropyl-5-(trifluoromethyl)-1-(3,4,5-trimethoxybenzoyl)-4,5-dihydro-1H-pyrazol-5-ol Depiction based on curated SMILES O HO F F F N N H 3 C H 3 C O CH 3 O O Acinetobacter Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett
Beta-Resorcylic acid Depiction based on curated SMILES OH OH O HO Campylobacter Regulation Preclinical (in vitro) Ammar AM, et al. 2020. Animals (Basel)
(E)-N'-(5-Bromo-2-hydroxybenzylidene)-3-methoxybenzohydrazide Depiction based on curated SMILES OH Br H 3 C N N H O O Chlamydia TTSS (Type III secretion system) Preclinical (in vitro) Dahlgren MK, et al. 2010. Bioorg Med Chem
N-[(E)-(5-tert-butyl-2-hydroxyphenyl)methylideneamino]-4-methylbenzamide Depiction based on curated SMILES OH CH 3 H 3 C H 3 C CH 3 N N H O Chlamydia TTSS (Type III secretion system) Preclinical (in vitro) Dahlgren MK, et al. 2010. Bioorg Med Chem
2-hydroxy-5-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzamide Depiction based on curated SMILES S OH N N NH 2 S O Enterococcus
Staphylococcus
Others; Adherence; Biofilm
Others; Adherence; Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Oniga SD, et al. 2017. Molecules
4-[(4Z)-4-(3-bromo-4-methoxybenzylidene)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid Depiction based on curated SMILES O Br F F F HO O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
5-(2,5-dimethyl-1H-pyrrol-1-yl)benzene-1,3-dicarboxylic acid Depiction based on curated SMILES CH 3 OH O HO O H 3 C N Mycobacterium Exoenzyme Preclinical (in vitro) Manger M, et al. 2005. Chembiochem
5-(acetylamino)-2-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid Depiction based on curated SMILES CH 3 HO O H 3 C O N H CH 3 N Mycobacterium Exoenzyme Preclinical (in vitro) Manger M, et al. 2005. Chembiochem
5-[3-[(E)-3-(3-hydroxy-2-methoxycarbonyl-4-nitrophenoxy)prop-1-enyl]phenyl]-1,2-oxazole-3-carboxylic acid Depiction based on curated SMILES HO O O N CH 3 O _ O O + N HO O O Mycobacterium Exoenzyme Preclinical (in vitro) Beresford NJ, et al. 2009. J Antimicrob Chemother
Isochroman-3-(S)-carboxylic acid methylester Depiction based on curated SMILES OH HO O O N H 3 C O O O Mycobacterium Exoenzyme Preclinical (in vitro) Beresford NJ, et al. 2009. J Antimicrob Chemother
   


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