|
3-cyclopropyl-5-(trifluoromethyl)-1-(3,4,5-trimethoxybenzoyl)-4,5-dihydro-1H-pyrazol-5-ol |
|
Acinetobacter |
Biofilm |
Preclinical (in vitro) |
Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett |
|
Beta-Resorcylic acid |
Depiction based on curated SMILES
OH
OH
O
HO
|
Campylobacter |
Regulation |
Preclinical (in vitro) |
Ammar AM, et al. 2020. Animals (Basel) |
|
(E)-N'-(5-Bromo-2-hydroxybenzylidene)-3-methoxybenzohydrazide |
Depiction based on curated SMILES
OH
Br
H
3
C
N
N
H
O
O
|
Chlamydia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Dahlgren MK, et al. 2010. Bioorg Med Chem |
|
N-[(E)-(5-tert-butyl-2-hydroxyphenyl)methylideneamino]-4-methylbenzamide |
Depiction based on curated SMILES
OH
CH
3
H
3
C
H
3
C
CH
3
N
N
H
O
|
Chlamydia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Dahlgren MK, et al. 2010. Bioorg Med Chem |
|
2-hydroxy-5-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzamide |
Depiction based on curated SMILES
S
OH
N
N
NH
2
S
O
|
Enterococcus Staphylococcus |
Others; Adherence; Biofilm Others; Adherence; Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Oniga SD, et al. 2017. Molecules
|
|
4-[(4Z)-4-(3-bromo-4-methoxybenzylidene)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid |
Depiction based on curated SMILES
O
Br
F
F
F
HO
O
H
3
C
N
N
O
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
5-(2,5-dimethyl-1H-pyrrol-1-yl)benzene-1,3-dicarboxylic acid |
Depiction based on curated SMILES
CH
3
OH
O
HO
O
H
3
C
N
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Manger M, et al. 2005. Chembiochem |
|
5-(acetylamino)-2-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid |
Depiction based on curated SMILES
CH
3
HO
O
H
3
C
O
N
H
CH
3
N
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Manger M, et al. 2005. Chembiochem |
|
5-[3-[(E)-3-(3-hydroxy-2-methoxycarbonyl-4-nitrophenoxy)prop-1-enyl]phenyl]-1,2-oxazole-3-carboxylic acid |
Depiction based on curated SMILES
HO
O
O
N
CH
3
O
_
O
O
+
N
HO
O
O
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Beresford NJ, et al. 2009. J Antimicrob Chemother |
|
Isochroman-3-(S)-carboxylic acid methylester |
Depiction based on curated SMILES
OH
HO
O
O
N
H
3
C
O
O
O
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Beresford NJ, et al. 2009. J Antimicrob Chemother |
|
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