|
(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[(5Z)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-4-oxo-2-phenylimino-1,3-thiazolidin-3-yl]-3-(4-phenylphenyl)propanoyl]amino]pentanamide |
|
Salmonella |
TTSS (SPI-1 encode) |
Preclinical (in vitro) |
Felise HB, et al. 2008. Cell Host Microbe |
|
Indole-3-acetic acid |
Depiction based on curated SMILES
O
OH
N
H
|
Salmonella |
TTSS (SPI-1 encode) |
Preclinical (in vitro) |
McShan AC, et al. 2016. ChemMedChem |
|
Fusaric acid |
Depiction based on curated SMILES
H
3
C
N
O
HO
|
Salmonella |
TTSS (SPI-1 encode) |
Preclinical (in vitro) |
Li J, et al. 2014. Biochem Biophys Res Commun |
|
N'-[(E)-(3-ethoxy-2-hydroxyphenyl)methylideneamino]oxamide |
Depiction based on curated SMILES
N
OH
O
NH
2
O
NH
H
3
C
O
|
Salmonella |
TTSS (SPI-1 encode); TTSS (SPI-2 encode) |
Preclinical (in vitro) |
Negrea A, et al. 2007. Antimicrob Agents Chemother |
|
N'-[(E)-(5-bromo-2-hydroxyphenyl)methylideneamino]oxamide |
Depiction based on curated SMILES
H
2
N
O
O
NH
N
Br
OH
|
Salmonella Shigella |
TTSS (SPI-1 encode); TTSS (SPI-2 encode) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Negrea A, et al. 2007. Antimicrob Agents Chemother Veenendaal AK, et al. 2009. J Bacteriol |
|
(E)-N'-(3,5-Dibromo-2-hydroxybenzylidene)nicotinohydrazide |
Depiction based on curated SMILES
N
OH
Br
O
Br
N
N
H
|
Chlamydia Escherichia Salmonella |
TTSS (Type III secretion system) TTSS (Type III secretion system) TTSS (SPI-1 encode); TTSS (SPI-2 encode) |
Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) |
Bailey L, et al. 2007. FEBS Lett Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem Negrea A, et al. 2007. Antimicrob Agents Chemother |
|
Nicotinic acid (5-bromo-2-hydroxy-benzylidene)-hydrazide |
Depiction based on curated SMILES
N
OH
O
Br
N
N
H
|
Salmonella Shigella |
TTSS (SPI-1 encode); TTSS (SPI-2 encode) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Negrea A, et al. 2007. Antimicrob Agents Chemother Veenendaal AK, et al. 2009. J Bacteriol |
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