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Compound category: Indolines
(total 4 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
[1-(1H-indol-3-yl)-1-oxopropan-2-yl] 2-(4-acetamidophenyl)-1,3-dioxoisoindole-5-carboxylate Depiction based on curated SMILES CH 3 O N H O O N H N CH 3 O O O Burkholderia
Yersinia		 Bsa T3SS
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vivo)		 Swietnicki W, et al. 2011. PLoS One
3-(6,6-dimethyl-3-oxotetrahydro-2H-pyran-2-yl)-3-hydroxy-1,3-dihydro-2H-indol-2-one Depiction based on curated SMILES O N H O CH 3 OH O CH 3 Pseudomonas Biofilm Preclinical (in vitro) von Ambüren J, et al. 2020. Microorganisms
3-hydroxy-3-[2-oxo-2-(pyridin-4-yl)ethyl]-1,3-dihydro-2H-indol-2-one Depiction based on curated SMILES OH N O HN O Pseudomonas Biofilm Preclinical (in vitro) von Ambüren J, et al. 2020. Microorganisms
4-[1,3-dioxo-5-(4-oxo-4H-3,1-benzoxazin-2-yl)-1,3-dihydro-2H-isoindol-2-yl]benzoic acid Depiction based on curated SMILES OH O O N O N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
   
   
   
   
   
   
   
   
   
   
   
   
   


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