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Compound category: Organoheterocyclic compounds
(total 30 related compounds in database, current show from 21 to 30)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Virstatin Depiction based on curated SMILES O HO O N O Acinetobacter
Vibrio
TFP (Type IV pili)
TCP (Toxin-coregulated pilus)
Preclinical (in vitro)
Preclinical (in vivo)
Nait Chabane Y, et al. 2014. BMC Microbiol
Hung DT, et al. 2005. Science
5-Bromo-2-(pyridin-4-yl)-1H-indole Depiction based on curated SMILES Br N H N Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol
5-fluoro-1-[3-(hydroxymethyl)-1,3-dihydro-2-benzofuran-1-yl]pyrimidine-2,4-dione Depiction based on curated SMILES HO F O O N O NH Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol; Na SH, et al. 2021. Int J Mol Sci
4-nonyl-1H-imidazol-2-ylamine hydrochloride Depiction based on curated SMILES H 3 C N N H H 2 N ClH Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Ballard TE, et al. 2008. Chemistry
5-tridecyl-1H-imidazol-2-amine;hydrochloride Depiction based on curated SMILES ClH H 2 N N H N CH 3 Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Ballard TE, et al. 2008. Chemistry
5-undecyl-1H-imidazol-2-amine;hydrochloride Depiction based on curated SMILES ClH H 2 N N H N CH 3 Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Ballard TE, et al. 2008. Chemistry
N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-pyrazol-3-yl)propanamide Depiction based on curated SMILES F F F N H O N N CH 3 N N H Acinetobacter
Salmonella
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Moshiri J, et al. 2018. Front Microbiol
N-[2-(2-amino-1H-imidazol-5-yl)phenyl]decanamide;hydrochloride Depiction based on curated SMILES ClH H 2 N N H N CH 3 HN O Acinetobacter Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-(4-bromophenyl)pyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES ClH Br NH 2 NH N N H O Br Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-phenylpyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES ClH H 2 N HN N N H O Br Br N Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
   


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