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Compound category: Organoheterocyclic compounds
(total 37 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(5R,6R)-5,6-bis[[4-(2-phenylethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N H N NH 2 Acinetobacter
Pseudomonas
Staphylococcus		 Biofilm
Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(2e)-3-(2-furyl)-N-[3-(hydroxymethyl)-4-morpholin-4-ylphenyl]acrylamide Depiction based on curated SMILES N H OH O O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
(2e)-N-(3-formyl-4-morpholin-4-ylphenyl)-3-(2-furyl)acrylamide Depiction based on curated SMILES N H O O O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
(2e)-N-(3-formyl-4-morpholin-4-ylphenyl)-3-(2-thienyl)acrylamide Depiction based on curated SMILES N H O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
(E)-N-[3-(hydroxymethyl)-4-morpholin-4-ylphenyl]-3-thiophen-2-ylprop-2-enamide Depiction based on curated SMILES N H OH S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
Pyridazinone, 2 Depiction based on curated SMILES O SH Cl CH 3 N N O Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
2',4-Diphenyl-2,4'-(p-phenylene)dithiazole Depiction based on curated SMILES N S N S Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
Phenazopyridine hydrochloride Depiction based on curated SMILES ClH NH 2 H 2 N N N N Staphylococcus TSST-1 (Toxic shock syndrome toxin-1) Preclinical (in vitro) Dufresne K, et al. 2024. J Biol Chem
4-(5-bromo-1-butylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N Br N NH 2 CH 3 N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1-ethylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
   


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