|
4-(5-bromo-1-propylindol-3-yl)pyrimidin-2-amine |
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(5-Bromo-1H-indol-3-yl)-N,N-dimethylpyrimidin-2-amine |
Depiction based on curated SMILES
N
Br
CH
3
N
H
N
H
3
C
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(5-bromo-1H-indol-3-yl)-N-ethylpyrimidin-2-amine |
Depiction based on curated SMILES
N
Br
H
3
C
N
H
N
NH
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(5-bromo-1H-indol-3-yl)-N-methylpyrimidin-2-amine |
Depiction based on curated SMILES
N
Br
CH
3
N
H
N
HN
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine |
Depiction based on curated SMILES
N
Br
NH
2
N
H
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(5-iodo-1H-indol-3-yl)pyrimidin-2-amine |
Depiction based on curated SMILES
N
I
NH
2
N
H
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(6-bromo-1-ethylindol-3-yl)pyrimidin-2-amine |
Depiction based on curated SMILES
Br
N
NH
2
H
3
C
N
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(6-bromo-1-methylindol-3-yl)pyrimidin-2-amine |
Depiction based on curated SMILES
NH
2
Br
N
CH
3
N
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
4-(6-bromo-1-propylindol-3-yl)pyrimidin-2-amine |
Depiction based on curated SMILES
Br
N
NH
2
H
3
C
N
N
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
Meridianin D |
Depiction based on curated SMILES
N
H
N
Br
NH
2
N
|
Mycobacterium Staphylococcus |
Biofilm Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem Huggins WM, et al. 2018. ACS Med Chem Lett |
|
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