|
Enzyme-IN-2 |
|
Helicobacter |
Urease |
Preclinical (in vitro) |
Maslanka M, et al. 2023. Eur J Med Chem |
|
4-(2-phosphonoethyl)catechol |
Depiction based on curated SMILES
P
O
OH
HO
OH
OH
|
Helicobacter |
Urease |
Preclinical (in vitro) |
Maslanka M, et al. 2023. Eur J Med Chem |
|
Compound 12 (internal name in literature) |
Depiction based on curated SMILES
HO
HO
PH
O
OH
O
OH
|
Helicobacter |
Urease |
Preclinical (in vitro) |
Maslanka M, et al. 2023. Eur J Med Chem |
|
Compound 18 (internal name in literature) |
Depiction based on curated SMILES
OH
HO
HO
O
OH
OH
O
O
P
|
Helicobacter |
Urease |
Preclinical (in vitro) |
Maslanka M, et al. 2023. Eur J Med Chem |
|
(3E)-3-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,4-tricarbonitrile |
Depiction based on curated SMILES
N
OH
HO
HO
N
H
2
N
N
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Fernández-Soto P, et al. 2021. Sci Rep |
|
N-[(Z)-(2,4-dihydroxyphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide |
Depiction based on curated SMILES
NH
OH
OH
N
O
HN
N
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
N'-[(Z)-(5-BROMO-2-HYDROXYPHENYL)METHYLIDENE]-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-3-CARBOHYDRAZIDE |
Depiction based on curated SMILES
HN
OH
Br
N
O
NH
N
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
(2Z,5Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-3-phenyl-2-(phenylimino)-1,3-thiazolidin-4-one |
Depiction based on curated SMILES
OH
CH
3
O
O
N
H
3
C
N
S
O
|
Salmonella Yersinia |
TTSS (SPI-1 encode) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Felise HB, et al. 2008. Cell Host Microbe
|
|
N-[(E)-(2,3,4-trihydroxyphenyl)methylideneamino]furan-2-carboxamide |
Depiction based on curated SMILES
HO
O
OH
HO
O
N
N
H
|
Salmonella Shigella |
TTSS (SPI-1 encode); TTSS (SPI-2 encode) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Negrea A, et al. 2007. Antimicrob Agents Chemother Veenendaal AK, et al. 2009. J Bacteriol |
|
Rhodanine, 1 |
Depiction based on curated SMILES
CH
3
S
S
HO
Br
_
O
O
+
N
H
3
C
O
N
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Suree N, et al. 2009. Bioorg Med Chem |
|
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