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Compound category: Phenols
(total 20 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Enzyme-IN-2 Depiction based on curated SMILES P OH OH OH O HO OH O Helicobacter Urease Preclinical (in vitro) Maslanka M, et al. 2023. Eur J Med Chem
4-(2-phosphonoethyl)catechol Depiction based on curated SMILES P O OH HO OH OH Helicobacter Urease Preclinical (in vitro) Maslanka M, et al. 2023. Eur J Med Chem
Compound 12
(internal name in literature)
Depiction based on curated SMILES HO HO PH O OH O OH Helicobacter Urease Preclinical (in vitro) Maslanka M, et al. 2023. Eur J Med Chem
Compound 18
(internal name in literature)
Depiction based on curated SMILES OH HO HO O OH OH O O P Helicobacter Urease Preclinical (in vitro) Maslanka M, et al. 2023. Eur J Med Chem
(3E)-3-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,4-tricarbonitrile Depiction based on curated SMILES N OH HO HO N H 2 N N Mycobacterium Exoenzyme Preclinical (in vitro) Fernández-Soto P, et al. 2021. Sci Rep
N-[(Z)-(2,4-dihydroxyphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide Depiction based on curated SMILES NH OH OH N O HN N Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
N'-[(Z)-(5-BROMO-2-HYDROXYPHENYL)METHYLIDENE]-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-3-CARBOHYDRAZIDE Depiction based on curated SMILES HN OH Br N O NH N Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
(2Z,5Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-3-phenyl-2-(phenylimino)-1,3-thiazolidin-4-one Depiction based on curated SMILES OH CH 3 O O N H 3 C N S O Salmonella
Yersinia
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
Felise HB, et al. 2008. Cell Host Microbe
N-[(E)-(2,3,4-trihydroxyphenyl)methylideneamino]furan-2-carboxamide Depiction based on curated SMILES HO O OH HO O N N H Salmonella
Shigella
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
Negrea A, et al. 2007. Antimicrob Agents Chemother
Veenendaal AK, et al. 2009. J Bacteriol
Rhodanine, 1 Depiction based on curated SMILES CH 3 S S HO Br _ O O + N H 3 C O N Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
   


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