Home
 Search
 Category
 Compounds
 Status
 Download
 Contacts
 Resources


Compound category: Azoles
(total 9 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
6-(2-chlorophenyl)-3-(4-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Depiction based on curated SMILES N Cl N S N N N Staphylococcus Others Preclinical (in vivo) Zhang J, et al. 2014. Proc Natl Acad Sci U S A
6-(3H-benzimidazol-5-yl)-3-pyridin-4-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Depiction based on curated SMILES N N N N HN S N N Staphylococcus Others Preclinical (in vivo) Zhang J, et al. 2014. Proc Natl Acad Sci U S A
Sodium 3-(3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)benzenesulfonate Depiction based on curated SMILES N S N N N O N + Na _ O O S Staphylococcus Others Preclinical (in vivo) Zhang J, et al. 2014. Proc Natl Acad Sci U S A
5beta,6alpha-Bis(4-cyclopentyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N H N N N N NH N N H NH 2 Acinetobacter
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[(4-tert-butyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N N H 2 N HN N N H 3 C CH 3 H 3 C N CH 3 H H N CH 3 H 3 C Acinetobacter
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(2-phenylethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N H N NH 2 Acinetobacter
Pseudomonas
Staphylococcus		 Biofilm
Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
2',4-Diphenyl-2,4'-(p-phenylene)dithiazole Depiction based on curated SMILES N S N S Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
5-methyl-2-phenyl-4-[(2,4,6-tribromophenyl)iminomethyl]-1H-pyrazole-3-thione Depiction based on curated SMILES Br Br Br N CH 3 HN N S Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
5-methyl-4-{[(4-nitrophenyl)amino]methylene}-2-phenyl-2,4-dihydro-3H-pyrazole-3-thione Depiction based on curated SMILES _ O O + N N H H 3 C S N N Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
   
   
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.






Back to top
2004-2025 NIPB, CAMS&PUMC