|
| 4-Methoxy-beta-nitrostyrene |
|
Shigella |
VirF |
Preclinical (in vitro) |
Hurt JK, et al. 2010. J Biomol Screen |
|
| 1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea |
|
Shigella |
VirF |
Preclinical (in vitro) |
Hurt JK, et al. 2010. J Biomol Screen; Emanuele AA, et al. 2014. J Antibiot (Tokyo); Emanuele AA, et al. 2015. PLoS One |
|
| 4-(2-(Pyrrolidin-1-yl)ethyl)aniline |
|
Shigella |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Dey S, et al. 2017. ChemMedChem |
|
| 4-chloro-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide |
|
Chlamydia
Salmonella
Shigella |
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
TTSS (Type III secretion system) |
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro) |
Muschiol S, et al. 2006. Proc Natl Acad Sci U S A
Negrea A, et al. 2007. Antimicrob Agents Chemother
Veenendaal AK, et al. 2009. J Bacteriol |
|
| 5-chloro-N-(3-chloro-4-methoxyphenyl)-2-(methylsulfonyl)pyrimidine-4-carboxamide |
|
Shigella |
VirF |
Preclinical (in vitro) |
Emanuele AA, et al. 2014. J Antibiot (Tokyo); Emanuele AA, et al. 2015. PLoS One |
|
| N-[(E)-(2,3,4-trihydroxyphenyl)methylideneamino]furan-2-carboxamide |
|
Salmonella
Shigella |
TTSS (SPI-1 encode); TTSS (SPI-2 encode)
TTSS (Type III secretion system) |
Preclinical (in vitro)
Preclinical (in vitro) |
Negrea A, et al. 2007. Antimicrob Agents Chemother
Veenendaal AK, et al. 2009. J Bacteriol |
|
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