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Compound category: Carboxylic acids and derivatives
(total 13 related compounds in database, current show from 11 to 13)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Guadinomine B Depiction based on curated SMILES N N NH 2 O H 2 N HO HO NH 2 NH 2 O CH 3 O HO N H CH 3 H 3 C NH O Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Iwatsuki M, et al. 2008. J Antibiot (Tokyo)
5-cyano-6-[(4-methylphenyl)methylsulfanyl]pyridine-2-carboxylic acid Depiction based on curated SMILES N N HO O CH 3 S Escherichia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Pan NJ, et al. 2009. Antimicrob Agents Chemother
(E)-N'-(3,5-Dibromo-2-hydroxybenzylidene)nicotinohydrazide Depiction based on curated SMILES N OH Br O Br N N H Chlamydia
Escherichia
Salmonella		 TTSS (Type III secretion system)
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Bailey L, et al. 2007. FEBS Lett
Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
Negrea A, et al. 2007. Antimicrob Agents Chemother
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   


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