|
(3R)-5-Oxo-6-(morpholinomethyl)-7-(1-naphthylmethyl)-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt |
|
Escherichia |
Type 1 fimbriae; P fimbriae |
Preclinical (in vivo) |
Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A |
|
(3R)-5-Oxo-6-(dimethylaminomethyl)-7-methyl-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt |
Depiction based on curated SMILES
CH
3
H
3
C
N
_
O
O
+
Li
S
H
N
O
CH
3
|
Escherichia |
Type 1 fimbriae; P fimbriae |
Preclinical (in vivo) |
Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A |
|
(3R)-5-Oxo-6-(morpholinomethyl)-7-(1-naphthylmethyl)-8-cyclopropyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt |
Depiction based on curated SMILES
N
O
O
N
_
O
O
H
S
+
Li
|
Escherichia |
Type 1 fimbriae; P fimbriae |
Preclinical (in vivo) |
Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A |
|
[3,4,5-triacetyloxy-6-[(R)-acetyloxy-(4-bromo-2-methylphenyl)methyl]oxan-2-yl]methyl acetate |
Depiction based on curated SMILES
O
Br
O
CH
3
O
CH
3
O
O
CH
3
O
H
O
O
O
H
3
C
O
CH
3
O
H
3
C
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
[3,4,5-triacetyloxy-6-[2-methyl-4-[3-(methylcarbamoyl)phenyl]phenoxy]oxan-2-yl]methyl acetate |
Depiction based on curated SMILES
O
O
CH
3
O
O
CH
3
O
CH
3
O
CH
3
NH
O
H
3
C
O
O
O
CH
3
O
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
[3,4,5-trihydroxy-6-[2-methyl-4-[3-(methylcarbamoyl)phenyl]phenoxy]oxan-2-yl]methyl 2-(dimethylamino)acetate |
Depiction based on curated SMILES
OH
O
N
CH
3
CH
3
HO
OH
CH
3
N
H
O
H
3
C
O
O
O
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
Guadinomine C1 |
Depiction based on curated SMILES
H
3
C
O
OH
H
H
H
3
C
H
N
N
NH
2
O
H
2
N
OH
HO
O
H
O
N
H
H
H
N
H
H
3
C
NH
H
CH
3
O
N
H
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine C2 |
Depiction based on curated SMILES
H
3
C
O
OH
H
H
H
3
C
H
N
N
NH
2
O
H
2
N
OH
HO
O
H
O
N
H
H
H
N
H
H
3
C
NH
H
CH
3
O
N
H
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine A |
Depiction based on curated SMILES
H
2
N
N
N
O
NH
2
OH
OH
OH
NH
2
NH
2
H
3
C
H
O
N
H
H
CH
3
CH
3
O
HO
N
H
O
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine D |
Depiction based on curated SMILES
N
N
H
2
N
O
NH
2
OH
OH
NH
2
N
H
O
H
3
C
H
3
C
H
O
N
H
H
CH
3
CH
3
O
OH
N
H
O
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
| | |