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Compound category: Indoles and derivatives
(total 17 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
SYG-180-2-2
(internal name in literature)
Depiction based on curated SMILES Se O N H HN Staphylococcus β-hemolysin Preclinical (in vivo) Rao L, et al. 2021. Front Microbiol; Rao L, et al. 2022. Front Cell Infect Microbiol
4-(5-bromo-1-butylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N Br N NH 2 CH 3 N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1-ethylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1-propylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-Bromo-1H-indol-3-yl)-N,N-dimethylpyrimidin-2-amine Depiction based on curated SMILES N Br CH 3 N H N H 3 C N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1H-indol-3-yl)-N-ethylpyrimidin-2-amine Depiction based on curated SMILES N Br H 3 C N H N NH Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1H-indol-3-yl)-N-methylpyrimidin-2-amine Depiction based on curated SMILES N Br CH 3 N H N HN Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N Br NH 2 N H N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-iodo-1H-indol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N I NH 2 N H N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(6-bromo-1-ethylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
   


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