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Compound category: Naphthalenes
(total 31 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-(4-naphthalen-2-ylphenyl)butan-2-one Depiction based on curated SMILES NH 2 NH N H O Brucella Others Preclinical (in vitro) Abdo MR, et al. 2011. Org Biomol Chem
Juglone Depiction based on curated SMILES O O OH Clostridium
Staphylococcus		 Collagenase
Others; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Nitulescu G, et al. 2022. Life (Basel)
Nitulescu G, et al. 2019. Drug Dev Res
4-naphthalen-1-yl-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole Depiction based on curated SMILES S S N N Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
2-(2-Pyridin-3-yl-vinyl)-3-m-tolyl-3H-quinazolin-4-one Depiction based on curated SMILES N O H 3 C N N Klebsiella Aerobactin Preclinical (in vitro) Bailey DC, et al. 2018. SLAS Discov
(3~{r})-8-Cyclopropyl-7-(Naphthalen-1-Ylmethyl)-5-Oxidanylidene-2,3-Dihydro-[1,3]thiazolo[3,2-A]pyridine-3-Carboxylic Acid Depiction based on curated SMILES O OH O S H N Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
(3~{R})-8-cyclopropyl-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES O H 3 C O HO H N S Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-(dimethylamino)-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES O H 3 C HO O S N CH 3 N Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-(dimethylamino)-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES HO O CH 3 H 3 C N S N O H 3 C Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES CH 3 O HO O S N O Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
N-(2,5-dimethylphenyl)-2-(4-oxo-3(4H)-quinazolinyl)acetamide Depiction based on curated SMILES O N N CH 3 O N H CH 3 Mycobacterium Immune modulation Preclinical (in vitro) Karanja CW, et al. 2021. ACS Infect Dis
   


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