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Compound category: Naphthalenes
(total 31 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-(furan-2-ylmethylcarbamoyl)-2-(4-oxobenzo[g]quinazolin-3-yl)acetamide Depiction based on curated SMILES O N H O HN O O N N Shigella TTSS (Type III secretion system) Preclinical (in vivo) Case HB, et al. 2020. Biochemistry
[2-[[(1R,2R)-2-methylcyclohexyl]carbamoylamino]-2-oxoethyl] 4-oxo-3-phenylphthalazine-1-carboxylate Depiction based on curated SMILES N N O O N H H H H 3 C O N H O O Shigella TTSS (Type III secretion system) Preclinical (in vivo) Case HB, et al. 2020. Biochemistry
Lapatinib Depiction based on curated SMILES O N NH F Cl S O O N H CH 3 O N Streptococcus Adherence Preclinical (in vivo) Manzer HS, et al. 2022. PLoS Pathog
3,5-Dihydroxy-2-naphthoic acid Depiction based on curated SMILES OH HO O OH Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
3,7-Dihydroxy-2-naphthoic acid Depiction based on curated SMILES OH O OH HO Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
4-Fluoro-1-naphthoic acid Depiction based on curated SMILES F O HO Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
2-benzyl-8-cyclopropyl-7-(1-naphthylmethyl)-5-oxo-thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES O N OH O S Escherichia Type 1 fimbriae; P fimbriae; S fimbriae Preclinical (in vivo) Greene SE, et al. 2014. mBio
1-(tert-butyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-napthyridine-3-carboxylic acid Depiction based on curated SMILES N Cl F O CH 3 HO O N H 3 C H 3 C Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol
[6,7-bis(chloranyl)-3-phosphono-quinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES OH OH O P OH OH O P N N Cl Cl Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
[6-(4-chlorophenyl)-3-phosphonoquinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES N Cl OH OH O P OH OH O P N Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
   


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