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April 10th, 2025


Compound category: Organic compounds
(total 903 related compounds in database, current show from 241 to 250)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-[3-(2-amino-1H-imidazol-5-yl)propyl]-4,5-dibromo-1-[(4-methoxyphenyl)methyl]pyrrole-2-carboxamide;hydrochloride Depiction based on curated SMILES Br ClH NH 2 HN N HN O Br H 3 C N O Acinetobacter Biofilm Preclinical (in vitro) Richards JJ, et al. 2008. Bioorg Med Chem Lett
5beta,6alpha-Bis[4-[(4,5-dibromo-1H-pyrrole-2-yl)carbonylaminomethyl]-1H-1,2,3-triazole-1-ylmethyl]-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N H N NH O N Br Br N H N N N H N H N NH 2 N H O Br Br HN Acinetobacter
Staphylococcus
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem
ZINC Lactate Depiction based on curated SMILES CH 3 O _ O HO CH 3 O _ O HO 2+ Zn Acinetobacter PNAG Preclinical (in vitro) Peng Q, et al. 2020. Sci Rep
Rifampicin Depiction based on curated SMILES CH 3 OH H 3 C HO CH 3 O O CH 3 CH 3 O H 3 C H 3 C OH OH N N N CH 3 CH 3 OH O NH CH 3 O O O Acinetobacter
Klebsiella
Biofilm
Capsule
Preclinical (in vitro)
Preclinical (in vitro)
Peng Q, et al. 2020. Sci Rep
Namikawa H, et al. 2019. Int J Antimicrob Agents
3-cyclopropyl-5-(trifluoromethyl)-1-(3,4,5-trimethoxybenzoyl)-4,5-dihydro-1H-pyrazol-5-ol Depiction based on curated SMILES O HO F F F N N H 3 C H 3 C O CH 3 O O Acinetobacter Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett
Oridonin Depiction based on curated SMILES H 3 C OH HO HO O O CH 2 OH H H H 3 C H H H H Aeromonas Biofilm; Motility Preclinical (in vitro) Wang L, et al. 2024. Microorganisms
Luteolin Depiction based on curated SMILES HO HO OH OH O O Aeromonas Aerolysin Preclinical (in vitro) Dong J, et al. 2021. Virulence
2-Hexyldecanoic acid Depiction based on curated SMILES OH O H 3 C CH 3 Aeromonas Aerolysin Preclinical (in vitro) Arumugam M, et al. 2023. Antibiotics (Basel)
H-Pyran-4-one-2,3 dihydro-3,5 dihydroxy-6-methyl Depiction based on curated SMILES CH 3 O O HO OH Aeromonas Aerolysin Preclinical (in vitro) Arumugam M, et al. 2023. Antibiotics (Basel)
Umbelliferone Depiction based on curated SMILES O O HO Aeromonas WhiB3 Preclinical (in vitro) Zhao L, et al. 2022. Int J Mol Sci
   


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