|
Compound 25 (internal name in literature) |
|
Chlamydia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Zigangirova NA, et al. 2012. Acta Naturae |
|
Compound 27 (internal name in literature) |
Depiction based on curated SMILES
O
S
F
F
F
CH
3
HN
O
N
N
OH
O
|
Chlamydia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Zigangirova NA, et al. 2012. Acta Naturae |
|
(2R)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-4-methylpentanamide |
Depiction based on curated SMILES
OH
HN
O
O
H
3
C
O
O
S
N
H
H
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2R,3R)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
HO
N
H
O
O
CH
3
O
O
S
HN
H
H
3
C
H
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2R,3R)-2-[[3-(2-chlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
CH
3
O
O
S
N
H
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxyhexanamide |
Depiction based on curated SMILES
HO
N
H
O
O
CH
3
O
O
S
HN
H
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(1-benzofuran-2-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
O
H
3
C
O
O
S
N
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,4-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,5-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,6-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
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