|
5-methyl-4-phenyl-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole |
|
Enterococcus Staphylococcus |
Others; Adherence; Biofilm Others; Adherence; Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Oniga SD, et al. 2017. Molecules
|
|
Epigallocatechin-3-gallate |
Depiction based on curated SMILES
HO
OH
OH
O
O
OH
OH
OH
H
H
O
OH
HO
|
Burkholderia Enterococcus Escherichia Pseudomonas |
Biofilm Biofilm; Others Biofilm Quorum sensing |
Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) |
Huber B, et al. 2003. Z Naturforsch C J Biosci Lee P, et al. 2015. Arch Oral Biol Lee KM, et al. 2009. J Food Prot
|
|
Guadinomine C1 |
Depiction based on curated SMILES
H
3
C
O
OH
H
H
H
3
C
H
N
N
NH
2
O
H
2
N
OH
HO
O
H
O
N
H
H
H
N
H
H
3
C
NH
H
CH
3
O
N
H
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine C2 |
Depiction based on curated SMILES
H
3
C
O
OH
H
H
H
3
C
H
N
N
NH
2
O
H
2
N
OH
HO
O
H
O
N
H
H
H
N
H
H
3
C
NH
H
CH
3
O
N
H
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine A |
Depiction based on curated SMILES
H
2
N
N
N
O
NH
2
OH
OH
OH
NH
2
NH
2
H
3
C
H
O
N
H
H
CH
3
CH
3
O
HO
N
H
O
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomine D |
Depiction based on curated SMILES
N
N
H
2
N
O
NH
2
OH
OH
NH
2
N
H
O
H
3
C
H
3
C
H
O
N
H
H
CH
3
CH
3
O
OH
N
H
O
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
Guadinomic acid |
Depiction based on curated SMILES
OH
HO
O
H
NH
2
NH
2
O
N
N
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Iwatsuki M, et al. 2008. J Antibiot (Tokyo) |
|
(E)-N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3-phenylprop-2-enamide;hydrochloride |
Depiction based on curated SMILES
ClH
H
2
N
N
H
N
N
H
O
|
Escherichia |
Biofilm |
Preclinical (in vitro) |
Bunders CA, et al. 2010. Bioorg Med Chem Lett |
|
1-N,3-N-dimethyl-5-[4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide |
Depiction based on curated SMILES
H
H
H
H
O
H
HO
HO
HO
OH
O
NH
CH
3
NH
O
CH
3
O
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vitro) |
Han Z, et al. 2010. J Med Chem |
|
Bio8B6 |
Depiction based on curated SMILES
HO
Cl
Cl
H
3
C
N
Cl
O
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Gauthier A, et al. 2005. Antimicrob Agents Chemother |
|
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