|
| 3-(3-chlorophenyl)-N-[(2S,3S)-1-(hydroxyamino)-3-methyl-1-oxopentan-2-yl]benzamide |
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
| 3-(4-nitrophenyl)furo[3,2-g]chromen-7-one |
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Patel KB, et al. 2018. Appl Environ Microbiol |
|
| 3-(furan-2-yl)-N-[(2S,3S)-1-(hydroxyamino)-3-methyl-1-oxopentan-2-yl]benzamide |
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
| 3-cyclohexyl-1-[4-(2-methoxyphenyl)piperazin-1-yl]propan-1-one |
|
Clostridium |
TcdB (Toxin B) |
Preclinical (in vitro) |
Farrow MA, et al. 2020. ACS Chem Biol |
|
| Amlodipine |
|
Clostridium |
TcdB (Toxin B) |
Preclinical (in vitro) |
Farrow MA, et al. 2020. ACS Chem Biol |
|
| Biochanin A |
|
Clostridium
Staphylococcus |
Collagenase
Others; Adherence; Biofilm |
Preclinical (in vitro)
Preclinical (in vitro) |
Nitulescu G, et al. 2022. Life (Basel)
Bai X, et al. 2023. Appl Microbiol Biotechnol |
|
| 5-acetyl-3-amino-4-(4-bromophenyl)-6-methyl-4,7-dihydrothieno[2,3-b]pyridine-2-carboxamide |
|
Clostridium |
TcdB (Toxin B) |
Preclinical (in vitro) |
Farrow MA, et al. 2020. ACS Chem Biol |
|
| 4',5-Dihydroxyflavone |
|
Clostridium |
Collagenase |
Preclinical (in vitro) |
Nitulescu G, et al. 2022. Life (Basel) |
|
| Juglone |
|
Clostridium
Staphylococcus |
Collagenase
Others; Biofilm |
Preclinical (in vitro)
Preclinical (in vitro) |
Nitulescu G, et al. 2022. Life (Basel)
Nitulescu G, et al. 2019. Drug Dev Res |
|
| 5-{3-[(2,4-difluorophenoxy)methyl]-4-methoxybenzylidene}-2,4,6(1H,3H,5H)-pyrimidinetrione |
|
Clostridium
Streptococcus |
theta-toxin/PFO (Perfringolysin O)
Pneumolysin |
Preclinical (in vitro)
Preclinical (in vitro) |
Aziz UBA, et al. 2024. Nat Commun
|
|
| | | |
