|
PB-2.12 (internal name in literature) |
|
Clostridium Streptococcus |
theta-toxin/PFO (Perfringolysin O) Pneumolysin |
Preclinical (in vitro) Preclinical (in vitro) |
Aziz UBA, et al. 2024. Nat Commun
|
|
Perphenazine |
Depiction based on curated SMILES
HO
Cl
S
N
N
N
|
Coxiella Legionella |
Dot/Icm T4SS Dot/Icm (Defect in organella trafficking/intracellular multiplication) |
Preclinical (in vitro) Preclinical (in vitro) |
Cheng E, et al. 2022. mBio
|
|
Roxindole |
Depiction based on curated SMILES
OH
HN
N
|
Coxiella Legionella |
Dot/Icm T4SS Dot/Icm (Defect in organella trafficking/intracellular multiplication) |
Preclinical (in vitro) Preclinical (in vitro) |
Cheng E, et al. 2022. mBio
|
|
5-(4-Phenoxybutoxy)psoralen |
Depiction based on curated SMILES
O
O
O
O
O
|
Coxiella Legionella |
Dot/Icm T4SS Dot/Icm (Defect in organella trafficking/intracellular multiplication) |
Preclinical (in vitro) Preclinical (in vitro) |
Cheng E, et al. 2022. mBio
|
|
Piperazinehexanamide derivative, 5 |
Depiction based on curated SMILES
N
H
O
CH
3
N
N
S
|
Coxiella Legionella |
Dot/Icm T4SS Dot/Icm (Defect in organella trafficking/intracellular multiplication) |
Preclinical (in vitro) Preclinical (in vitro) |
Cheng E, et al. 2022. mBio
|
|
Etamivan |
Depiction based on curated SMILES
H
3
C
N
CH
3
O
HO
O
H
3
C
|
Coxiella Legionella |
Dot/Icm T4SS Dot/Icm (Defect in organella trafficking/intracellular multiplication) |
Preclinical (in vitro) Preclinical (in vitro) |
Cheng E, et al. 2022. mBio
|
|
Ursolic acid |
Depiction based on curated SMILES
H
3
C
H
CH
3
H
3
C
OH
CH
3
H
H
CH
3
CH
3
O
HO
H
CH
3
H
H
|
Enterococcus |
Biofilm |
Preclinical (in vitro) |
Silva GNSD, et al. 2019. Biomolecules |
|
Asiatic acid |
Depiction based on curated SMILES
CH
3
H
H
H
3
C
HO
HO
HO
CH
3
H
H
H
3
C
H
3
C
O
OH
H
CH
3
H
H
|
Enterococcus |
Biofilm |
Preclinical (in vitro) |
Wojnicz D, et al. 2017. Adv Clin Exp Med |
|
Proanthocyanidin |
Depiction based on curated SMILES
OH
H
H
O
H
HO
OH
OH
OH
OH
O
OH
H
CH
3
O
OH
HO
|
Enterococcus |
Biofilm |
Preclinical (in vitro) |
Yang SY, et al. 2020. Int Endod J |
|
Oleanolic acid |
Depiction based on curated SMILES
H
3
C
H
CH
3
O
OH
CH
3
H
3
C
H
3
C
CH
3
OH
H
H
H
3
C
H
|
Enterococcus |
Biofilm |
Preclinical (in vitro) |
Shirlaw O, et al. 2020. Antibiotics (Basel) |
|
| | |