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Compound category: Organic compounds
(total 903 related compounds in database, current show from 381 to 390)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
PB-2.12
(internal name in literature)
Depiction based on curated SMILES H 2 N Cl Cl O NH 2 O H 3 C O O Clostridium
Streptococcus
theta-toxin/PFO (Perfringolysin O)
Pneumolysin
Preclinical (in vitro)
Preclinical (in vitro)
Aziz UBA, et al. 2024. Nat Commun
Perphenazine Depiction based on curated SMILES HO Cl S N N N Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
Roxindole Depiction based on curated SMILES OH HN N Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
5-(4-Phenoxybutoxy)psoralen Depiction based on curated SMILES O O O O O Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
Piperazinehexanamide derivative, 5 Depiction based on curated SMILES N H O CH 3 N N S Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
Etamivan Depiction based on curated SMILES H 3 C N CH 3 O HO O H 3 C Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
Ursolic acid Depiction based on curated SMILES H 3 C H CH 3 H 3 C OH CH 3 H H CH 3 CH 3 O HO H CH 3 H H Enterococcus Biofilm Preclinical (in vitro) Silva GNSD, et al. 2019. Biomolecules
Asiatic acid Depiction based on curated SMILES CH 3 H H H 3 C HO HO HO CH 3 H H H 3 C H 3 C O OH H CH 3 H H Enterococcus Biofilm Preclinical (in vitro) Wojnicz D, et al. 2017. Adv Clin Exp Med
Proanthocyanidin Depiction based on curated SMILES OH H H O H HO OH OH OH OH O OH H CH 3 O OH HO Enterococcus Biofilm Preclinical (in vitro) Yang SY, et al. 2020. Int Endod J
Oleanolic acid Depiction based on curated SMILES H 3 C H CH 3 O OH CH 3 H 3 C H 3 C CH 3 OH H H H 3 C H Enterococcus Biofilm Preclinical (in vitro) Shirlaw O, et al. 2020. Antibiotics (Basel)
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



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