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 April 11th, 2025


Compound category: Organic compounds
(total 903 related compounds in database, current show from 441 to 450)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
1-[3-(2-amino-1H-imidazol-5-yl)phenyl]-3-(3,4-dichlorophenyl)urea Depiction based on curated SMILES H 2 N HN N Cl Cl NH O N H Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-dichlorobenzamide Depiction based on curated SMILES NH 2 Cl Cl O N H N H N Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
(4Z)-2-benzyl-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-(benzyloxy)benzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES F F F O N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
(4Z)-4-benzylidene-2-phenyl-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES F F F O N N Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-bromo-4-methoxybenzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
(4Z)-4-[(4-chlorophenyl)methylidene]-2-phenyl-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES F F F N Cl O N Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
3-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-3-(trifluoromethyl)pyrazol-1-yl]-N-(2-hydroxyethyl)benzamide Depiction based on curated SMILES Br F F F OH NH O CH 3 O N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
3-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-3-(trifluoromethyl)pyrazol-1-yl]benzoic acid Depiction based on curated SMILES O Br F F F HO O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
4-[(4Z)-4-(3-bromo-4-methoxybenzylidene)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid Depiction based on curated SMILES O Br F F F HO O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
   


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