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Compound category: Organic compounds
(total 903 related compounds in database, current show from 481 to 490)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
8-(dimethylamino)-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES O H 3 C HO O S N CH 3 N Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-(dimethylamino)-7-[(2,3-dimethylphenyl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES N CH 3 H 3 C CH 3 N S O HO O CH 3 Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-(dimethylamino)-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES HO O CH 3 H 3 C N S N O H 3 C Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES CH 3 O HO O S N O Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
lithium;(3R)-8-cyclopropyl-5-oxo-7-(quinolin-3-ylmethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylate Depiction based on curated SMILES N O + Li _ O O S H N Listeria PrfA (Pleiotropic regulatory factor) Preclinical (in vitro) Kulén M, et al. 2018. J Med Chem
6-N-Hydroxylaminopurine Depiction based on curated SMILES N N H N N NH HO Listeria Regulation Preclinical (in vitro) Krajewski SS, et al. 2017. Nucleic Acids Res
(2R)-2-[(5Z)-4-oxo-5-[(4-phenylmethoxycarbonylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid Depiction based on curated SMILES O O S S H O HO N O Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
(2R)-2-[(5Z)-5-[(4-methoxycarbonylphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid Depiction based on curated SMILES OH O H S S CH 3 N O O O Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
(2Z)-2-[1-[5-(1H-pyrrol-2-yl)-2-furyl]ethylidene]pyrrole Depiction based on curated SMILES NH O CH 3 N Mycobacterium Exoenzyme Preclinical (in vitro) Manger M, et al. 2005. Chembiochem
(2Z)-5-[5-[(2Z)-hexa-2,5-dien-2-yl]-1H-pyrrol-2-yl]-2-[(5-hex-5-enyl-1H-pyrrol-2-yl)methylidene]-3-methoxypyrrole Depiction based on curated SMILES H 3 C O H 2 C N H CH 3 N N H H 2 C Mycobacterium Exoenzyme Preclinical (in vitro) Manger M, et al. 2005. Chembiochem
   


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