|
N-(5-chloro-2-methylphenyl)-2-(4-oxo-3(4H)-quinazolinyl)acetamide |
|
Mycobacterium |
Immune modulation |
Preclinical (in vitro) |
Karanja CW, et al. 2021. ACS Infect Dis |
|
N-[(FURAN-2-YL)METHYL]-N'-{1-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]-1-(THIOPHEN-2-YL)PROPAN-2-YL}ETHANEDIAMIDE |
Depiction based on curated SMILES
O
O
H
3
C
HN
O
HN
O
S
N
CH
3
N
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Chen L, et al. 2010. ACS Med Chem Lett |
|
N-[(Z)-(2,4-dihydroxyphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide |
Depiction based on curated SMILES
NH
OH
OH
N
O
HN
N
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
N-[(Z)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide |
Depiction based on curated SMILES
N
H
N
CH
2
O
N
H
N
HO
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
N'-[(Z)-(5-BROMO-2-HYDROXYPHENYL)METHYLIDENE]-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-3-CARBOHYDRAZIDE |
Depiction based on curated SMILES
HN
OH
Br
N
O
NH
N
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
1-[2-[(4-fluorophenyl)methylamino]-2-oxo-ethyl]-N-[1-(4-methyl-5-vinyl-1H-imidazol-2-yl)ethyl]-6-oxo-pyridine-3-carboxamide |
Depiction based on curated SMILES
H
2
C
F
NH
O
CH
3
O
N
O
NH
H
3
C
N
H
N
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Mori M, et al. 2014. Bioorg Med Chem Lett |
|
S-(2,4-difluorophenyl) 2-[5-[4-(trifluoromethyl)phenyl]tetrazol-2-yl]ethanethioate |
Depiction based on curated SMILES
O
F
F
F
F
F
S
N
N
N
N
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl][(1R,2S,6S)-6-(2,4-dihydroxyphenyl)-2-[4-[(1E)-2-(2,4-dihydroxyphenyl)ethenyl]-2,6-dihydroxyphenyl]-4-methyl-3-cyclohexen-1-yl]methanone |
Depiction based on curated SMILES
HO
H
3
C
CH
3
OH
HO
OH
OH
OH
H
H
H
CH
3
HO
OH
O
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Mascarello A, et al. 2013. PLoS One |
|
3-{[4-(dimethylamino)-2-pyridin-3-yl-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]carbonyl}phenol |
Depiction based on curated SMILES
O
N
OH
CH
3
N
N
N
H
3
C
N
|
Mycobacterium |
Immune modulation |
Preclinical (in vitro) |
Karanja CW, et al. 2021. ACS Infect Dis |
|
(4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl)difluoromethylphosphonic acid |
Depiction based on curated SMILES
HO
OH
O
P
F
F
F
F
F
Br
F
F
F
NH
O
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Rawls KA, et al. 2009. Bioorg Med Chem Lett |
|
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