|
MAC-545496 |
|
Staphylococcus |
Regulation; Biofilm |
Preclinical (in vivo) |
El-Halfawy OM, et al. 2020. Nat Chem Biol |
|
Sodium 3-(3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)benzenesulfonate |
Depiction based on curated SMILES
N
S
N
N
N
O
N
+
Na
_
O
O
S
|
Staphylococcus |
Others |
Preclinical (in vivo) |
Zhang J, et al. 2014. Proc Natl Acad Sci U S A |
|
SYG-180-2-2 (internal name in literature) |
Depiction based on curated SMILES
Se
O
N
H
HN
|
Staphylococcus |
β-hemolysin |
Preclinical (in vivo) |
Rao L, et al. 2021. Front Microbiol; Rao L, et al. 2022. Front Cell Infect Microbiol |
|
YH7 (internal name in literature) |
Depiction based on curated SMILES
O
Se
Se
O
N
|
Staphylococcus |
Biofilm |
Preclinical (in vivo) |
Xiao Y, et al. 2024. mSphere |
|
Alnustone |
Depiction based on curated SMILES
O
|
Streptococcus |
Pneumolysin |
Preclinical (in vivo) |
Zhang C, et al. 2022. Fitoterapia |
|
Curcumin |
Depiction based on curated SMILES
OH
HO
H
3
C
O
H
3
C
O
O
O
|
Acinetobacter Bacillus Clostridium Enterococcus Pseudomonas |
BfmRS Biofilm Collagenase Biofilm Quorum sensing |
Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) Preclinical (in vitro) |
Raorane CJ, et al. 2019. Front Microbiol Fernandes S, et al. 2023. Food Res Int Nitulescu G, et al. 2022. Life (Basel) Oda DF, et al. 2019. Int Endod J
|
|
Azithromycin |
Depiction based on curated SMILES
H
3
C
OH
CH
3
O
CH
3
CH
3
O
O
CH
3
N
H
3
C
CH
3
OH
CH
3
HO
H
3
C
H
3
C
H
3
C
HO
H
3
C
OH
N
H
3
C
O
O
CH
3
O
O
|
Acinetobacter |
Biofilm |
Preclinical (in vitro) |
Peng Q, et al. 2020. Sci Rep |
|
(5R,6R)-5,6-bis[(4-benzyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine |
Depiction based on curated SMILES
N
H
N
N
N
N
N
H
N
H
N
H
2
N
|
Acinetobacter Pseudomonas |
Biofilm Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Huigens RW 3rd, et al. 2009. Org Biomol Chem
|
|
5beta,6alpha-Bis(4-butyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine |
Depiction based on curated SMILES
N
N
N
H
2
N
N
H
N
N
H
3
C
N
H
3
C
H
H
N
|
Acinetobacter |
Biofilm |
Preclinical (in vitro) |
Huigens RW 3rd, et al. 2009. Org Biomol Chem |
|
5beta,6alpha-Bis(4-cyclohexyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine |
Depiction based on curated SMILES
N
H
N
N
N
N
N
H
N
N
H
NH
2
|
Acinetobacter Pseudomonas |
Biofilm Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Huigens RW 3rd, et al. 2009. Org Biomol Chem
|
|
| | |