|
(2R,3S,4S,5S,6R)-2-[(R)-hydroxy-(4-isoquinolin-5-yl-2-methylphenyl)methyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
(2R,3S,4S,5S,6R)-2-[(R)-[4-(1-aminoisoquinolin-7-yl)-2-methylphenyl]-hydroxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
Depiction based on curated SMILES
HO
OH
OH
OH
O
HO
H
CH
3
NH
2
N
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
(2R,3S,4S,5S,6R)-2-[4-(1-aminoisoquinolin-7-yl)-2-methylphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
Depiction based on curated SMILES
HO
OH
OH
OH
O
O
CH
3
NH
2
N
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
Aurodox |
Depiction based on curated SMILES
O
CH
3
O
OH
HO
OH
H
3
C
H
N
O
OH
OH
OH
H
3
C
H
3
C
CH
3
O
H
H
H
H
H
3
C
CH
3
NH
O
H
H
H
3
C
O
CH
3
H
H
H
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vivo) |
Kimura K, et al. 2011. J Antibiot (Tokyo) |
|
1-N,3-N-dimethyl-5-[3-(trifluoromethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide |
Depiction based on curated SMILES
F
O
O
HO
F
HO
HO
OH
NH
NH
O
O
CH
3
CH
3
F
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Cusumano CK, et al. 2011. Sci Transl Med |
|
1-N,3-N-dimethyl-5-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide |
Depiction based on curated SMILES
OH
HO
HO
HO
O
O
CH
3
CH
3
NH
O
O
NH
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Cusumano CK, et al. 2011. Sci Transl Med |
|
2-benzyl-8-cyclopropyl-7-(1-naphthylmethyl)-5-oxo-thiazolo[3,2-a]pyridine-3-carboxylic acid |
Depiction based on curated SMILES
O
N
OH
O
S
|
Escherichia |
Type 1 fimbriae; P fimbriae; S fimbriae |
Preclinical (in vivo) |
Greene SE, et al. 2014. mBio |
|
3-[3-chloro-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-N-methylbenzamide |
Depiction based on curated SMILES
O
OH
OH
HO
HO
H
3
C
O
Cl
O
NH
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Cusumano CK, et al. 2011. Sci Transl Med |
|
3-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]-N-methylbenzamide |
Depiction based on curated SMILES
O
OH
OH
HO
HO
H
3
C
OH
H
O
NH
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
3-[4-[(R)-hydroxy-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-N-methylbenzamide |
Depiction based on curated SMILES
O
CH
3
HO
OH
OH
OH
CH
3
HO
H
O
N
H
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| | |