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Compound category: Organic compounds
(total 903 related compounds in database, current show from 131 to 140)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(2R,3S,4S,5S,6R)-2-[(R)-hydroxy-(4-isoquinolin-5-yl-2-methylphenyl)methyl]-6-(hydroxymethyl)oxane-3,4,5-triol Depiction based on curated SMILES HO OH OH OH O HO H CH 3 N Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
(2R,3S,4S,5S,6R)-2-[(R)-[4-(1-aminoisoquinolin-7-yl)-2-methylphenyl]-hydroxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol Depiction based on curated SMILES HO OH OH OH O HO H CH 3 NH 2 N Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
(2R,3S,4S,5S,6R)-2-[4-(1-aminoisoquinolin-7-yl)-2-methylphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol Depiction based on curated SMILES HO OH OH OH O O CH 3 NH 2 N Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
Aurodox Depiction based on curated SMILES O CH 3 O OH HO OH H 3 C H N O OH OH OH H 3 C H 3 C CH 3 O H H H H H 3 C CH 3 NH O H H H 3 C O CH 3 H H H Escherichia TTSS (Type III secretion system) Preclinical (in vivo) Kimura K, et al. 2011. J Antibiot (Tokyo)
1-N,3-N-dimethyl-5-[3-(trifluoromethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide Depiction based on curated SMILES F O O HO F HO HO OH NH NH O O CH 3 CH 3 F Escherichia Type 1 fimbriae Preclinical (in vivo) Cusumano CK, et al. 2011. Sci Transl Med
1-N,3-N-dimethyl-5-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide Depiction based on curated SMILES OH HO HO HO O O CH 3 CH 3 NH O O NH Escherichia Type 1 fimbriae Preclinical (in vivo) Cusumano CK, et al. 2011. Sci Transl Med
2-benzyl-8-cyclopropyl-7-(1-naphthylmethyl)-5-oxo-thiazolo[3,2-a]pyridine-3-carboxylic acid Depiction based on curated SMILES O N OH O S Escherichia Type 1 fimbriae; P fimbriae; S fimbriae Preclinical (in vivo) Greene SE, et al. 2014. mBio
3-[3-chloro-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-N-methylbenzamide Depiction based on curated SMILES O OH OH HO HO H 3 C O Cl O NH Escherichia Type 1 fimbriae Preclinical (in vivo) Cusumano CK, et al. 2011. Sci Transl Med
3-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]-N-methylbenzamide Depiction based on curated SMILES O OH OH HO HO H 3 C OH H O NH Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
3-[4-[(R)-hydroxy-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-N-methylbenzamide Depiction based on curated SMILES O CH 3 HO OH OH OH CH 3 HO H O N H Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
   


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