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 April 6th, 2025


Compound category: Organoheterocyclic compounds
(total 4 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Perphenazine Depiction based on curated SMILES HO Cl S N N N Coxiella
Legionella		 Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)		 Preclinical (in vitro)
Preclinical (in vitro)		 Cheng E, et al. 2022. mBio
Roxindole Depiction based on curated SMILES OH HN N Coxiella
Legionella		 Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)		 Preclinical (in vitro)
Preclinical (in vitro)		 Cheng E, et al. 2022. mBio
N4-isobutyl-N2-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine Depiction based on curated SMILES N S CH 3 N H N N N H H 3 C Legionella Dot/Icm (Defect in organella trafficking/intracellular multiplication) Preclinical (in vitro) Cheng E, et al. 2022. mBio
Piperazinehexanamide derivative, 5 Depiction based on curated SMILES N H O CH 3 N N S Coxiella
Legionella		 Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)		 Preclinical (in vitro)
Preclinical (in vitro)		 Cheng E, et al. 2022. mBio
   
   
   
   
   
   
   
   
   
   
   
   
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.






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