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Compound category: Organoheterocyclic compounds
(total 322 related compounds in database, current show from 61 to 70)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(5R,6R)-5,6-bis[(4-tert-butyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N N H 2 N HN N N H 3 C CH 3 H 3 C N CH 3 H H N CH 3 H 3 C Acinetobacter
Staphylococcus
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(2-phenylethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N H N NH 2 Acinetobacter
Pseudomonas
Staphylococcus
Biofilm
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem

(5R,6R)-5,6-bis[[4-(3-methylbutyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N H 3 C CH 3 N N H H 2 N N N N CH 3 N H 3 C H H Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(cyclohexylmethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N N H N H N H 2 N Acinetobacter Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(cyclopentylmethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N N H NH 2 Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(phenoxymethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES O N N H N N N N HN N H NH 2 O Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Huigens RW 3rd, et al. 2009. Org Biomol Chem
1-(tert-butyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-napthyridine-3-carboxylic acid Depiction based on curated SMILES N Cl F O CH 3 HO O N H 3 C H 3 C Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol
Gallein Depiction based on curated SMILES HO OH O HO HO O O Acinetobacter
Klebsiella
Others; Biofilm
Others; Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Roberge N, et al. 2021. Front Microbiol
3,4,5-trimethoxy-N-(5,5,6,6-tetramethylbenzo[b][1]benzazepin-11-yl)benzamide Depiction based on curated SMILES N H O CH 3 O H 3 C O H 3 C O H 3 C CH 3 N CH 3 CH 3 Acinetobacter Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2015. Bioorg Med Chem Lett
3-(2-amino-1H-imidazol-5-yl)-N-tridecan-7-ylpropanamide;hydrochloride Depiction based on curated SMILES CH 3 ClH H 2 N N H N O N H CH 3 Acinetobacter
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Ballard TE, et al. 2008. Chemistry
   


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