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Compound category: Azoles
(total 88 related compounds in database, current show from 31 to 40)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]adamantane-1-carboxamide;hydrochloride Depiction based on curated SMILES ClH NH 2 N H N NH O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
1-[3-(2-amino-1H-imidazol-5-yl)phenyl]-3-(3,4-dichlorophenyl)urea Depiction based on curated SMILES H 2 N HN N Cl Cl NH O N H Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
(4Z)-4-benzylidene-2-phenyl-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES F F F O N N Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
(4-bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl imidothiocarbamate Depiction based on curated SMILES H 2 N NH S Br H 3 C N O N Helicobacter Flagella Preclinical (in vitro) Suerbaum S, et al. 2022. mBio
3-[5-chloro-2-(3-sulfopropylsulfanyl)-1,3-benzothiazol-3-ium-3-yl]propane-1-sulfonic acid Depiction based on curated SMILES HO O O S OH O O S S S + N Cl Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
S-(2,4-difluorophenyl) 2-[5-[4-(trifluoromethyl)phenyl]tetrazol-2-yl]ethanethioate Depiction based on curated SMILES O F F F F F S N N N N Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
(2Z)-2-(3-chloro-5-ethoxy-4-hydroxybenzylidene)-7,8-dimethyl[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one Depiction based on curated SMILES H 3 C OH Cl O N H 3 C CH 3 N S O Pseudomonas
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Harmon DE, et al. 2010. Antimicrob Agents Chemother
5beta,6alpha-Bis(4-cyclopropyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES H 2 N N H N N N N H H N N N Pseudomonas Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
(E)-3-(4-Acetyl-phenyl)-N-[4-(1-hydroxy-6-nitro-1H-benzoimidazol-2-yl)-phenyl]-acrylamide Depiction based on curated SMILES N + N O _ O N HO H 3 C N H O O Pseudomonas TTSS (Type III secretion system) Preclinical (in vitro) Marsden AE, et al. 2016. Antimicrob Agents Chemother
(E)-3-(4-acetylphenyl)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide Depiction based on curated SMILES HO N N N H 3 C N H O O Pseudomonas TTSS (Type III secretion system) Preclinical (in vitro) Marsden AE, et al. 2016. Antimicrob Agents Chemother
   


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