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Compound category: Azoles
(total 88 related compounds in database, current show from 71 to 80)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Chlorzoxazone Depiction based on curated SMILES O N H Cl O Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
Pirlindole mesylate Depiction based on curated SMILES HO O O S CH 3 CH 3 HN N Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
Fenbendazole Depiction based on curated SMILES S CH 3 N H N N H O O Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
N-[2-[4-(benzimidazol-1-yl)anilino]-2-oxoethyl]-3-chloro-1-benzothiophene-2-carboxamide Depiction based on curated SMILES N H N N O S Cl O N H Salmonella
Yersinia
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vivo)
Boonyom R, et al. 2022. J Genet Eng Biotechnol
Swietnicki W, et al. 2011. PLoS One
5-Chloro-2-phenoxymethyl-1H-benzoimidazole Depiction based on curated SMILES O Cl N H N Shigella VirF Preclinical (in vitro) Emanuele AA, et al. 2014. J Antibiot (Tokyo); Emanuele AA, et al. 2015. PLoS One
5-methyl-2-phenyl-4-[(2,4,6-tribromophenyl)iminomethyl]-1H-pyrazole-3-thione Depiction based on curated SMILES Br Br Br N CH 3 HN N S Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
5-methyl-4-{[(4-nitrophenyl)amino]methylene}-2-phenyl-2,4-dihydro-3H-pyrazole-3-thione Depiction based on curated SMILES _ O O + N N H H 3 C S N N Staphylococcus Others Preclinical (in vitro) Suree N, et al. 2009. Bioorg Med Chem
3-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol Depiction based on curated SMILES N H F F F OH N Vibrio Post-translational modification Preclinical (in vitro) Wang G, et al. 2022. ChemMedChem
Isonaamine A Depiction based on curated SMILES HO N H 2 N OH N Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
Isonaamine D Depiction based on curated SMILES N HO H 2 N N CH 3 O Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
   


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