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Compound category: Azoles
(total 88 related compounds in database, current show from 41 to 50)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(E)-3-(4-fluorophenyl)-N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]prop-2-enamide Depiction based on curated SMILES HO N _ O O + N N O N H F Pseudomonas
Yersinia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vivo)		 Marsden AE, et al. 2016. Antimicrob Agents Chemother
Kim OK, et al. 2009. J Med Chem
Garrity-Ryan LK, et al. 2010. Infect Immun
1-{(E)-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)imino]methyl}naphthalen-2-ol Depiction based on curated SMILES N OH H 3 C CH 3 N N Pseudomonas
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Harmon DE, et al. 2010. Antimicrob Agents Chemother
2,2,2-trifluoro-N-[2-[2-(4-iodoanilino)-2-oxoethyl]sulfanyl-3H-benzimidazol-5-yl]acetamide Depiction based on curated SMILES F I NH N H F O F O HN N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide Depiction based on curated SMILES NH O O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylsulfanyl)-N-(3,4-dichlorophenyl)acetamide Depiction based on curated SMILES Cl Cl NH N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylthio)-N-[3-(methylthio)phenyl]acetamide Depiction based on curated SMILES S N H N CH 3 O N H S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylsulfanyl)-N-(4-bromophenyl)acetamide Depiction based on curated SMILES Br HN N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
Acetamide, 2-(1H-benzimidazol-2-ylthio)-N-(4-chlorophenyl)- Depiction based on curated SMILES Cl HN N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
2-(1H-benzimidazol-2-ylsulfanyl)-N-(4-cyanophenyl)acetamide Depiction based on curated SMILES N H N N S O N H Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
Acetamide, 2-(1H-benzimidazol-2-ylthio)-N-phenyl- Depiction based on curated SMILES NH N H O N S Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
   


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