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Compound category: Carboxylic acids and derivatives
(total 13 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(3R)-5-Oxo-6-(morpholinomethyl)-7-(1-naphthylmethyl)-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt Depiction based on curated SMILES O _ O O N + Li N O H S Escherichia Type 1 fimbriae; P fimbriae Preclinical (in vivo) Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A
(3R)-5-Oxo-6-(dimethylaminomethyl)-7-methyl-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt Depiction based on curated SMILES CH 3 H 3 C N _ O O + Li S H N O CH 3 Escherichia Type 1 fimbriae; P fimbriae Preclinical (in vivo) Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A
(3R)-5-Oxo-6-(morpholinomethyl)-7-(1-naphthylmethyl)-8-cyclopropyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt Depiction based on curated SMILES N O O N _ O O H S + Li Escherichia Type 1 fimbriae; P fimbriae Preclinical (in vivo) Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A
[3,4,5-triacetyloxy-6-[(R)-acetyloxy-(4-bromo-2-methylphenyl)methyl]oxan-2-yl]methyl acetate Depiction based on curated SMILES O Br O CH 3 O CH 3 O O CH 3 O H O O O H 3 C O CH 3 O H 3 C Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
[3,4,5-triacetyloxy-6-[2-methyl-4-[3-(methylcarbamoyl)phenyl]phenoxy]oxan-2-yl]methyl acetate Depiction based on curated SMILES O O CH 3 O O CH 3 O CH 3 O CH 3 NH O H 3 C O O O CH 3 O Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
[3,4,5-trihydroxy-6-[2-methyl-4-[3-(methylcarbamoyl)phenyl]phenoxy]oxan-2-yl]methyl 2-(dimethylamino)acetate Depiction based on curated SMILES OH O N CH 3 CH 3 HO OH CH 3 N H O H 3 C O O O Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
Guadinomine C1 Depiction based on curated SMILES H 3 C O OH H H H 3 C H N N NH 2 O H 2 N OH HO O H O N H H H N H H 3 C NH H CH 3 O N H H Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Iwatsuki M, et al. 2008. J Antibiot (Tokyo)
Guadinomine C2 Depiction based on curated SMILES H 3 C O OH H H H 3 C H N N NH 2 O H 2 N OH HO O H O N H H H N H H 3 C NH H CH 3 O N H H Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Iwatsuki M, et al. 2008. J Antibiot (Tokyo)
Guadinomine A Depiction based on curated SMILES H 2 N N N O NH 2 OH OH OH NH 2 NH 2 H 3 C H O N H H CH 3 CH 3 O HO N H O Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Iwatsuki M, et al. 2008. J Antibiot (Tokyo)
Guadinomine D Depiction based on curated SMILES N N H 2 N O NH 2 OH OH NH 2 N H O H 3 C H 3 C H O N H H CH 3 CH 3 O OH N H O Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Iwatsuki M, et al. 2008. J Antibiot (Tokyo)
   


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